Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Anacortes, WA

I am suppose to start rituxan but very worried where I read that blood pressure goes up and what to do. I have borderline high blood pressure at home but really high in drs. I am not on meds as the ones i have tried drop it too low at home, but this past two weeks with all the pain in top of my feet and the weight gain from doing nothing the pressure has been around 149/85 at home and at drs even higher. My RA says it is from the inflammation that it is going up and to gfo ahead and start the… read more

July 16
 · 
Be the first to react
A myRAteam Member

I have discussed all this with the RA dr, she said the ativan will keep me calm and hlep pressure, but I told her it is from the Steriod NOT anxiety, she said she would lower it to 80 rather than a 100 , but i reacted to a 40 mg ijection in my knee with higher blood pressure but not as high as it is now even without meds, and headace for 5 daysa and 5 days of ativan i don't think i would like. I react to xanax .025 knocks me out and she wants me to do 0,5 of ativan or lorazapam and go up from there, it is not solving the probelm of high blood pressure just hiding the side effects to a degree

July 16
myRAteam

These are really valid concerns, and it's great that you're being so proactive about understanding what's ahead. Your rheumatologist's point about inflammation driving up blood pressure actually makes a lot of sense — when RA inflammation is active, it can affect artery elasticity and raise blood pressure. Treating the RA Show Full Answer

These are really valid concerns, and it's great that you're being so proactive about understanding what's ahead. Your rheumatologist's point about inflammation driving up blood pressure actually makes a lot of sense — when RA inflammation is active, it can affect artery elasticity and raise blood pressure. Treating the RA effectively could actually help bring those numbers down over time.

Regarding Rituxan specifically, it is not typically associated with raising blood pressure the way some other RA medications are. TNF inhibitors and biologics like Rituxan are generally considered less likely to contribute to high blood pressure compared to NSAIDs or steroids. The steroid concern is completely understandable given your sensitivity. It's worth knowing that before each Rituxan infusion, a corticosteroid is typically given through an IV to help prevent infusion reactions. Since you've flagged steroid sensitivity, make sure your rheumatologist has a clear plan for managing that specifically on infusion day.

Some things worth discussing with both your rheumatologist and primary doctor include:

- Monitoring blood pressure closely on infusion day and the days following
- Flagging your steroid sensitivity so the pre-infusion steroid dose can be carefully managed
- Asking about blood pressure medication options that won't drop your pressure too low at home — there are several types, and finding the right fit may take some trial and error with your doctor's guidance
- Discussing the Ativan concern openly — your hesitation about dependency is completely reasonable and worth voicing clearly to your doctor A myRAteam member shared a similar experience, noting that pain and stress during flares noticeably elevated their blood pressure, and another member confirmed that enduring pain puts real stress on both body and mind — so the foot pain you're experiencing could absolutely be contributing right now.

Your Tuesday appointment with your primary doctor is a great opportunity to lay everything out — the steroid sensitivity, the fainting history, and the upcoming Rituxan infusion. Going in with a written list of concerns can help make sure nothing gets missed. You're clearly thinking about this carefully, which is exactly the right approach. 😊

July 16

Related Questions

View All
A myRAteam Member asked a question 💭
Montreal, QC