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Symptoms of Rheumatoid Arthritis

Medically reviewed by Ariel D. Teitel, M.D., M.B.A.
Written by Kelly Crumrin
Updated on July 22, 2022

Rheumatoid arthritis (RA) affects each person a little differently. Symptoms depend on the severity of the condition and can appear or disappear at any time. Symptoms worsen during exacerbations (called flares) and may subside during periods of remission. RA is a progressive disease, meaning joint damage tends to worsen over time. Joint damage caused by RA cannot be reversed.

Although most people think of RA as a disease of the joints, it is actually a systemic disease that can cause inflammation in many parts of the body. Treatment can effectively manage many RA symptoms and slow progression.

Joint Symptoms of Rheumatoid Arthritis

RA typically impacts the joints symmetrically — affecting the same joint on both sides of the body. Joints commonly affected include the hands, feet, wrists, elbows, ankles, and knees. Joints are often swollen, stiff, warm, reddened, and painful. Left untreated, RA can cause joint damage that may lead to deformity and disability. Stiffness can be more intense in the morning or after a period of inactivity. Baker’s cysts — painless swellings also called popliteal cysts — may form behind the knees.

Skin Symptoms of Rheumatoid Arthritis

RA can cause skin rashes, ulcers, and the development of rheumatoid nodules — firm lumps under the skin.

Learn more about RA rashes.

Watch rheumatologist Dr. Ashira Blazer walk through meditation techniques that can help ease arthritis symptoms.

Eye Symptoms of Rheumatoid Arthritis

As a systemic disease that impacts the whole body, RA can cause episcleritis, scleritis, conjunctivitis, and uveitis. These types of eye inflammation can involve pain, redness, vision changes, and light sensitivity. Left untreated, scleritis and uveitis can progress and lead to loss of vision.

Learn more about how RA affects the eyes.

General Symptoms of Rheumatoid Arthritis

Fatigue is a very common symptom of rheumatoid arthritis due to high levels of inflammation in the body. Rheumatoid arthritis can also be associated with anemia, or low red blood cell count, which can contribute to fatigue. RA can also cause abnormal bleeding. Depression and anxiety are common for people with RA, as they are for people living with any chronic disease. Some people with RA experience weight loss.

Complications of Rheumatoid Arthritis

Rheumatoid arthritis can promote inflammation anywhere in the body, leading to problems such as vasculitis (inflammation of the blood vessels), which can cause life-threatening organ damage. Pericarditis, or inflammation of the membrane surrounding the heart, is another potential complication of RA that can cause chest pain. RA can also cause inflammation of the lungs resulting in chest pain, cough, and shortness of breath.

People with RA are more likely to develop heart disease, diabetes, hypertension (high blood pressure), and high cholesterol, particularly if they are obese. Lifestyle changes such as losing weight, stopping smoking, and eating a balanced diet can help counteract the risk.

At What Age Do Rheumatoid Arthritis Symptoms Appear?

In the majority of cases, rheumatoid arthritis is diagnosed in people between ages 30 and 60. However, a juvenile form of RA may develop in children under age 17.

Do Rheumatoid Arthritis Symptoms Go Away?

Rheumatoid arthritis symptoms may appear during a flare and diminish during a remission period. Rheumatoid arthritis is a chronic condition that does not currently have a cure. In most people, symptoms can be effectively treated with medication and lifestyle changes.

What Does Rheumatoid Arthritis Look Like?

Rheumatoid arthritis can show up as swollen or disfigured joints, such as toes that curl up (clawed toes) or that twist and overlap with one another, or fingers that twist and point outward.

Condition Guide

Updated on July 22, 2022

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My Doctor Will Not Give Me Any Pain Meds, Then I Get Depressed From The Constant Pain. I Just Get Tired Of Being In Pain All Of The Time
January 7, 2024 by A myRAteam Member 2 answers
My Dr Just Put Me On Simponi With My Methotrexate. Is Anyone Else Tried This Combination? How Long Does It Usually Take To Work?
January 9, 2024 by A myRAteam Member 4 answers
My Doctor Tells Me Many Of The Additional Symptoms Listed In This Article Are Not Related To My RA - Is That Common With Some Dr's?
April 16, 2024 by A myRAteam Member 3 answers
Ariel D. Teitel, M.D., M.B.A. is the clinical associate professor of medicine at the NYU Langone Medical Center in New York. Review provided by VeriMed Healthcare Network. Learn more about him here.
Kelly Crumrin is a senior editor at MyHealthTeam and leads the creation of content that educates and empowers people with chronic illnesses. Learn more about her here.

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