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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

percentage of RA patients developing lymphomas

A myRAteam Member asked a question 💭
Shawnee Mission, KS

Diagnosed with RA 13 years ago at the age of 73, my RA doctor put me on put me on
methotrexate and Hydroxychloroquine
Managed RA off and on all those years. In January this year I found an enlarged lymph node on my neck. Long story short, biopsy confirmed Non Hodgkins Lymphoma from
RA and MTX medicine. Between 1 and 4 people with RA will develop lymphomas. This is a rare happening, and I am being treated with immunotherapy. My prognosis is good. My posting this experience is to be aware… read more

June 2
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Reactions
A myRAteam Member

Lori I'm so sorry to hear this. I'm so happy you have a good prognosis. Please keep us updated. Scary stuff. Prayers!

June 2
A myRAteam Member

I am so sorry @A myRAteam Member

June 2
myRAteam

Thank you so much for sharing your experience — it takes real courage to open up about something so serious, and your awareness could genuinely help others. Wishing you all the best with your treatment and that positive prognosis! 💙

To add some context around the numbers: while RA does carry a modestly elevated lymphoma Show Full Answer

Thank you so much for sharing your experience — it takes real courage to open up about something so serious, and your awareness could genuinely help others. Wishing you all the best with your treatment and that positive prognosis! 💙

To add some context around the numbers: while RA does carry a modestly elevated lymphoma risk, the general population has roughly a 2% risk of developing non-Hodgkin lymphoma, and for people with RA that rises to around 4%. So while the risk is doubled, it remains relatively uncommon overall. Your advice about persistent lymph nodes is spot-on. Key warning signs to watch for include:

- A lymph node that remains enlarged for more than a few weeks or months
- Unexplained fever or weight loss
- Unusual fatigue
- Night sweats

High disease activity in RA and certain medications, including methotrexate, have been linked to a higher lymphoma risk. As a myRAteam member shared from their own experience, catching changes early and speaking with a doctor promptly makes a real difference.

Anyone noticing a lymph node that simply won't go away should bring it to their rheumatologist or physician's attention without delay.

June 2
A myRAteam Member

Lori, I know this is so scary for you. However, being given a good prognosis is very encouraging. I will place you on my prayer list, as we all need prayers. Best wishes to you. I’ve added you to my team and hope you will keep us posted on your recovery.

June 2

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