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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Greenville, NC

Like when wind or water or you get touched it feels like sandpaper across your skin? I take methotrexate and prednisone but not sure if its a medicine symptom or RA symptom.

April 11
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A myRAteam Member

Yes! I have this without steroid usage. I am taking Rinvoq. My skin sensitivity has been an issue no matter the meds.

April 13
myRAteam

Is sensitive skin a side effect of methotrexate or prednisone, or is it related to RA itself?

Sensitive skin that feels like sandpaper when touched could be related to both your RA and your medications. Methotrexate can cause various skin-related side effects, including itchy or discolored skin. Some myRAteam members have Show Full Answer

Is sensitive skin a side effect of methotrexate or prednisone, or is it related to RA itself?

Sensitive skin that feels like sandpaper when touched could be related to both your RA and your medications. Methotrexate can cause various skin-related side effects, including itchy or discolored skin. Some myRAteam members have reported experiencing uncomfortable skin sensations while taking methotrexate.

RA itself can also affect the nerves and cause unusual skin sensations. Up to 20 percent of people with RA experience symptoms in their nerves and skin, which can include painful sensations, tingling, or extreme sensitivity to touch. This is sometimes related to peripheral neuropathy, which can cause a prickling feeling, pins-and-needles sensation, or painful and unusual sensations in the skin.

Since both your RA and methotrexate could be contributing to your sensitive skin, it's important to discuss this symptom with your rheumatologist. They can help determine the cause and recommend appropriate treatment or adjustments to your medications if needed.

If you notice any severe skin reactions like peeling, blisters, or rash, contact your doctor right away, as these can be serious side effects of methotrexate.

April 11

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