Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has anyone with RA taken a GLP1 drug with good results?

A myRAteam Member asked a question 💭
White Lake, MI
March 20
 · 
Reactions
A myRAteam Member

Thank you very much!

March 22
A myRAteam Member

@A myRAteam Member yes! I am Diabetic Type 2 and I do the Mounjaro self injection pen. I take it for diabetes but I have also lost 38 pounds!!! Full disclosure, I also take Farxiga, I take Enbrel injections for RA, I take Celecoxib for inflammation and a few others for other ailments like high blood pressure etc, but these are the main drugs and afflictions. I feel pretty good honestly. I deal with what I would consider a pain level 1 most of the time and sometimes a pain level of 2 unless I have a Flare. If you want to do a GLP-1 strictly for weight loss - I think you'll be fine but that being said - I would Highly Advise you consult and get a prescription from your Dr. I would never (for myself) purchase something like a GLP-1 drug off the internet. You want the genuine product from a genuinely trusted Dr and Pharmacy. Best of Luck Red! Let me know how it goes!!! I will be Rooting for ya!!

March 21
myRAteam

Have people with RA had good results with GLP-1 drugs?

Yes, recent research shows promising results. In a study of people with RA who were overweight or had obesity, those taking GLP-1 drugs like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) experienced several benefits over up to one year:

- Greater Show Full Answer

Have people with RA had good results with GLP-1 drugs?

Yes, recent research shows promising results. In a study of people with RA who were overweight or had obesity, those taking GLP-1 drugs like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) experienced several benefits over up to one year:

- Greater reductions in RA disease activity
- Less joint pain
- More weight loss
- Lower inflammatory markers (C-reactive protein and erythrocyte sedimentation rate)
- Improved cholesterol and blood sugar levels

Interestingly, the improvements in pain and inflammation weren't strongly tied to weight loss alone, suggesting these drugs may reduce inflammation through other pathways.

Important considerations:

About one-third of participants stopped the medication, mainly due to gastrointestinal side effects like nausea or stomach upset, and insurance or cost issues.

GLP-1 drugs aren't currently approved to treat RA specifically. They're approved for type 2 diabetes, weight loss, and cardiovascular risk reduction. If you're considering this option, discuss it with your rheumatologist or healthcare provider to see if it might fit your overall treatment plan.

March 20

Related Questions

View All

Does anyone with rheumatoid arthritis take the GLP1 medication?

A myRAteam Member asked a question 💭
White Lake, MI
August 19, 2025

How My Service Dog Has Changed My Life With RA
Managing Stress With RA
Improving Sleep with RA