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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
San Diego, CA
October 2, 2025
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Based on the search results, methotrexate is actually considered a first-line treatment for RA, recommended by the American College of Rheumatology. About 60% of people diagnosed with RA are currently taking or have taken methotrexate because it effectively reduces inflammation and helps slow disease progression.

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Based on the search results, methotrexate is actually considered a first-line treatment for RA, recommended by the American College of Rheumatology. About 60% of people diagnosed with RA are currently taking or have taken methotrexate because it effectively reduces inflammation and helps slow disease progression.

While it's natural to be concerned about starting methotrexate, many myRAteam members report positive experiences. One member shared they've been on it for two years with good results, while another has used it successfully for four years. The medication typically shows results within 3-6 weeks and can improve:
• Joint swelling and tenderness
• Disability levels
• Quality of life
• Protection against joint damage

It's important to discuss any concerns about medication choices with your rheumatologist, who can explain the benefits and risks of different treatment options for your specific situation.

October 2, 2025

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