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What supplements have been helpful while taking methotrexate?

Folic acid is the most commonly recommended supplement for people taking methotrexate. It can significantly reduce common side effects like nausea, mouth sores, and other gastrointestinal issues. Studies show it may reduce the risk of these side effects by up to Show Full Answer

What supplements have been helpful while taking methotrexate?

Folic acid is the most commonly recommended supplement for people taking methotrexate. It can significantly reduce common side effects like nausea, mouth sores, and other gastrointestinal issues. Studies show it may reduce the risk of these side effects by up to 79 percent.

Your rheumatologist will determine the right dosage for you, which could be:
- 1 milligram daily
- 5 milligrams once per week
- Another dosage based on your specific needs

A myRAteam member shared, "Folic acid is a must while taking methotrexate." Another member noted, "My doctor increased my dosage of folic acid, and I haven't had any [mouth sores] since."

Folic acid can also help lower the risk of liver problems while on methotrexate. It's important to take it exactly as prescribed by your doctor and discuss the timing with them, as they'll guide you on when to take it in relation to your methotrexate dose.

Before starting any supplement, always speak with your healthcare provider to ensure the right dose and confirm it won't interfere with your treatment plan.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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