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A myRAteam Member asked a question 💭
Missouri City, TX

Hello family i wanted to know if anyone have been diagnose with liver disease having RA. If so what has been the out come and what meds are you taking…. My new Rheumatologist has orderd me to have alot of blood work and suggested i have my liver checked. I wasnt aware that RA affects the liver…

April 26, 2023
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Answer Summary

Members responded warmly to a question about autoimmune liver disease and RA, sharing their own diagnoses and experiences with conditions like... Read more

Members responded warmly to a question about autoimmune liver disease and RA, sharing their own diagnoses and experiences with conditions like autoimmune hepatitis, fatty liver, and elevated liver enzymes. Several members highlighted the importance of regular blood work, with many getting labs done every 3 months, and shared experiences with medications like Methotrexate, Actemra, Leflunomide, and Imuran, noting that folic acid is often taken alongside MTX to help protect the liver. A recurring theme was the need to stay proactive, communicate openly with doctors, and lean on community support when navigating the overlap between RA and liver health.

A myRAteam Member

@A myRAteam Member....sorry late to the post....just saw yours. Methotrexate was the 1st DMARD my dr tried when I was 1st diagnosed. Unfortunately it did not work for me even at a max dose of 20mg/week. It did however wreck havoc on my red blood cells, despite taking 3 mg of Folic Acid. So had to stop taking it. I'm taking different meds now, but still taking Folic Acid 3mg. The meds I'm on now don't require it like Methotrexate did, but my dr and I agreed to stay on the Folic Acid as my red blood cell production never yet has recovered. Folic acid can't hurt you,...it's water soluble... so it's better to have more than not enough. You can safely go up to 5mg/day. The only reason they max it at 5mg/day even though you technically can't OD on it is because they've found that at doses higher than 5mg/day most people will start getting GI upset issues....and basically who wants that along with all the other crap we deal with daily with our RA alone...lol

June 20, 2023 (edited)
A myRAteam Member

Thanks Brenda
I’m take MTX too and I’m noticing pain in my mid back and right sided pain below my breast. I was just upped last week to 15mg and starting Saturday I have vomiting , nausea feeling icky. I see my Dr next week might need to ask about changing medication.

May 2, 2023
A myRAteam Member

MTX can also mess with your heart, liver and kidneys. I took it for 4 weeks, 1 time a week, and cut it, as I noticed my kidneys operating at about 1/2 of normal. I also had nausea, vomiting and just horrid feeling yuck. I am still taking Hydroxacloquine and the only side effect so far is dry eyes.

April 26, 2023
A myRAteam Member

Hi Denine - I'm on Methotrexate and get my liver checked every few months as well. RA effects ALL areas of our body including our organs.

https://www.arthritis.org/diseases/more-about/h...

April 26, 2023
A myRAteam Member

The medication to treat your RA will affect your liver. Too many NSAIDs as well. A close friend does have an auto immune disease that affects the liver which she went yellow - luckily she's all good now and it's all being managed. I get my bloodwork done every 3 months. Stay ahead of the game. :) Best wishes. I call my RA Dracula.

June 28, 2023

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