What is the prognosis for seronegative rheumatoid arthritis?
The outlook for seronegative RA is generally considered to be similar to — or in some cases milder than — seropositive RA, though it really depends on the individual. Here's what's generally known: Potentially milder course
- Some evidence suggests seronegative Show Full Answer
What is the prognosis for seronegative rheumatoid arthritis?
The outlook for seronegative RA is generally considered to be similar to — or in some cases milder than — seropositive RA, though it really depends on the individual. Here's what's generally known: Potentially milder course
- Some evidence suggests seronegative RA may follow a milder disease path than seropositive RA
- People with seronegative RA may respond better to traditional RA medications like DMARDs
Similar progression over time
- Both types can progress similarly over the long term
- Seronegative RA is still a progressive condition, meaning symptoms can worsen without treatment
- Some people initially diagnosed as seronegative later develop antibodies, which can shift their diagnosis
Early treatment is key
- Starting treatment as early as possible gives the best chance of preserving joint function and quality of life
- One myRAteam member shared: "After many years of damage, the blood tests show nothing. They call it seronegative RA. We just go by the damage seen on imaging... We have to stay ahead of the damage with these new biologics."
Overall prognosis depends on factors like genetics, how quickly treatment begins, and how well the condition is managed. Staying in close contact with a rheumatologist is the best way to keep things on track.
May 12
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