I've had flares that subsided within 24 hours; I've also had flares that lasted multiple days. Depending on how my flares are (pain or just exhaustion), determines how I cope. Either way, I rest, but if my flare is painful, I'll take some Tylenol and try to get myself moving when the Tylenol is working. If my flare is pure exhaustion, I crawl back into bed. My last flare was exhaustion, so I got back in bed, fell asleep and woke up feeling better. Self care is always key. I'm still in the process of not sweating the small stuff and I try not to take myself too seriously. I have depression and anxiety, so laughter is a huge help!