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A myRAteam Member asked a question 💭
WIGSTON LEICESTER

I have active synovial inflammation in my hands which look awful

3 hours ago
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A myRAteam Member

Ha ha try getting an appointment especially as my last scan showed the inflammation!

3 hours ago
myRAteam

That sounds really frustrating, especially when you're dealing with visible, active inflammation. It's completely understandable to want more aggressive treatment.

Biologics are typically considered when other disease-modifying antirheumatic drugs (DMARDs) haven't provided enough relief first. Doctors usually try medications Show Full Answer

That sounds really frustrating, especially when you're dealing with visible, active inflammation. It's completely understandable to want more aggressive treatment.

Biologics are typically considered when other disease-modifying antirheumatic drugs (DMARDs) haven't provided enough relief first. Doctors usually try medications like methotrexate, hydroxychloroquine, leflunomide, or sulfasalazine before moving to biologics. There's also a screening process required before starting biologics to make sure it's safe. Doctors need to rule out underlying or silent infections, since biologics work by suppressing parts of the immune system, which can increase infection risk. Common pre-screening tests include:

- Tuberculosis (TB) test
- Hepatitis B and C blood tests
- Liver enzyme tests
- Complete blood count
- Cholesterol/lipid levels

If any of these flag a concern, that could delay prescribing biologics until the issue is addressed.

The best step is to have a direct conversation with your rheumatologist asking specifically what criteria need to be met before biologics are considered for you. You deserve a clear answer!

3 hours ago

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