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I have longstanding seropositive rheumatoid arthritis, recently confirmed as active and untreated by ultrasound after a long period of uncertainty. My blood work shows several markers elevated β€” inflammatory markers, along with rising liver enzymes (AST/ALT) that have been climbing across multiple tests. Because of this, my treatment is on hold β€” I need Hepatology clearance before starting a biologic, but my scheduled appointment is months away.

Given the urgency of active, untreated RA, I'm… read more

2 days ago
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A myRAteam Member

In my area, getting appointments with specialists always seems to come with a delay β€” my process with Stanford actually started back in May, and I'm still waiting for answers. Because of this, I'm looking into remote second opinion services like Cedars-Sinai. Does anyone have experience with these, and do you think they're actually useful?

I'd appreciate any advice on questions to ask, or how to know if a second opinion is a right move.

1 day ago
myRAteam

What a frustrating situation β€” active, confirmed RA on one side, and a months-long wait blocking treatment on the other. That tension is completely understandable, and pursuing a second opinion is a very reasonable move.

Seeking a second opinion is not only normal, it can genuinely accelerate your path to treatment. It can Show Full Answer

What a frustrating situation β€” active, confirmed RA on one side, and a months-long wait blocking treatment on the other. That tension is completely understandable, and pursuing a second opinion is a very reasonable move.

Seeking a second opinion is not only normal, it can genuinely accelerate your path to treatment. It can open doors to additional diagnostic methods, alternative specialists, or a faster route to clearance. Here are some practical steps that may help move things along:

- Ask your rheumatologist to flag urgency β€” Request that they formally document the active, untreated RA status and communicate directly with hepatology about the time-sensitive nature of your case. Sometimes a physician-to-physician call can accelerate a referral.
- Request a cancellation slot β€” Ask to be placed on a cancellation list for your hepatology appointment. Openings do come up.
- Explore virtual second opinions β€” Major centers like Cleveland Clinic and Massachusetts General Hospital offer virtual consultations, which can be faster and reduce travel costs.
- Ask your primary care doctor for alternative referrals β€” They may know of hepatologists with shorter wait times or different health systems worth exploring.
- Check your insurance β€” Many insurers cover second opinions, so it's worth a quick call before paying out of pocket. When you do see a specialist, some useful questions to ask include:

- What is the most likely cause of the rising AST/ALT given my RA history?
- Is there a threshold at which biologics could be considered safe to start?
- Can liver function be monitored closely enough to allow a cautious trial of treatment?
- Are there any RA treatments that carry lower liver risk that could be considered in the interim?

It's also worth knowing that regular liver enzyme monitoring is standard practice when starting biologics β€” so having a hepatologist involved is actually a protective step, not just a bureaucratic one. A myRAteam member shared a similar experience of feeling scared and uncertain about delayed treatment, but found that once the path forward became clearer, the anxiety eased significantly. You're advocating for yourself in exactly the right way β€” that matters enormously with a condition like RA.

2 days ago

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