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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 16
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Chin acne specifically isn't a well-documented side effect of methotrexate for RA. However, skin-related changes can happen while taking it, since the medication affects fast-growing cells throughout the body — including skin cells.

Some known skin-related side effects of methotrexate include:

- Mouth sores or ulcers
- Show Full Answer

Chin acne specifically isn't a well-documented side effect of methotrexate for RA. However, skin-related changes can happen while taking it, since the medication affects fast-growing cells throughout the body — including skin cells.

Some known skin-related side effects of methotrexate include:

- Mouth sores or ulcers
- Rash
- Changes in skin texture It's really worth bringing this up with a rheumatologist, since they can determine whether the acne is linked to methotrexate or something else entirely. They may also suggest taking folic acid supplements, which help counteract some of methotrexate's effects on fast-growing cells and reduce side effects.

Never adjust or stop methotrexate without consulting a doctor first, as this could affect RA management.

August 16

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