Do you think a bone marrow transplant help in Pannus conditions?
I think in some southern countries are offering such treatments?
May 5
Pannus is inflamed synovial tissue that grows in the joints due to RA, but the good news is that it's not permanent β it can be reversed with proper treatment.
The main goal is to treat the underlying RA itself. Here are the key approaches:
- DMARDs (Disease-Modifying Antirheumatic Drugs) β These are the backbone of RA Show Full Answer
Pannus is inflamed synovial tissue that grows in the joints due to RA, but the good news is that it's not permanent β it can be reversed with proper treatment.
The main goal is to treat the underlying RA itself. Here are the key approaches:
- DMARDs (Disease-Modifying Antirheumatic Drugs) β These are the backbone of RA treatment and help slow or stop the inflammation driving pannus growth
- Biologics β Target specific cells and signals (like tumor necrosis factor) involved in joint destruction
- JAK inhibitors β Another class of medication that helps control the immune response
- NSAIDs and steroids β Help manage inflammation and pain, though they're typically used alongside DMARDs rather than alone Researchers are also working on treatments that specifically target the cells involved in pannus formation, such as FLS cells, T cells, B cells, and osteoclasts. These advances could make future treatments even more precise and effective.
As always, working closely with a rheumatologist to find the right treatment plan is the best path forward. Keeping RA well-controlled is the most powerful way to limit pannus growth and protect your joints long-term.
May 5