What antibiotics can be safely taken for UTIs while on methotrexate, and can any be used long-term?
When taking methotrexate for rheumatoid arthritis, UTIs require careful attention. Your rheumatologist may temporarily pause your methotrexate while you're on antibiotics to help your immune system fight the infection more Show Full Answer
What antibiotics can be safely taken for UTIs while on methotrexate, and can any be used long-term?
When taking methotrexate for rheumatoid arthritis, UTIs require careful attention. Your rheumatologist may temporarily pause your methotrexate while you're on antibiotics to help your immune system fight the infection more effectively.
It's important to know that certain antibiotics can interact with methotrexate. Specifically, sulfamethoxazole-trimethoprim (sold as Bactrim or Septra) - commonly used for UTIs and respiratory infections - can increase methotrexate's side effects or toxicity.
Make sure your doctors know about all medications you're taking. Your healthcare team can help identify safe antibiotic options that won't cause dangerous interactions with methotrexate.
Don't delay treating UTI symptoms. Waiting increases the risk of kidney and bladder infections, and can lead to recurring UTIs. Contact your doctor at the first sign of symptoms so they can prescribe appropriate treatment and determine whether to continue your methotrexate during antibiotic therapy.
The decision about which antibiotic to use and for how long depends on your specific situation and should be made by your healthcare provider based on the severity of your infection and your complete medication profile.
February 26
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