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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
January 13
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myRAteam

How many people with RA are on Humira, and can it cause depression?

It's great to hear you're doing well! Many people with RA use Humira as part of their treatment plan, though specific numbers aren't available in the community discussions.

Regarding depression and biologics like Humira, it's important to know that Show Full Answer

How many people with RA are on Humira, and can it cause depression?

It's great to hear you're doing well! Many people with RA use Humira as part of their treatment plan, though specific numbers aren't available in the community discussions.

Regarding depression and biologics like Humira, it's important to know that depression is very common with RA itself—affecting up to 41% of people with the condition. Depression can stem from:

- Living with chronic pain and reduced mobility
- Worry about disease progression
- The overall impact of managing a chronic illness

While biologics like Humira aren't typically known to cause depression directly, some RA medications (particularly corticosteroids like Prednisone) can worsen mood symptoms.

If you're experiencing depression or mood changes, it's worth discussing with your doctor. They can help determine whether it's related to your medication or the condition itself, and explore treatment options that may include antidepressants, therapy, or lifestyle changes.

A myRAteam member shared experiences with Humira, and many members discuss both their treatments and mental health openly in the community.

January 13
A myRAteam Member

check with your dr right away. I dont want you to have a lapse in treatment

January 13
A myRAteam Member

I have been on Rinvoq for five year's and it has been a God send to me, and I have just now started to get stiffness again

January 13
A myRAteam Member

Humira is used by millions of people. Depression isn’t common with it, but some people do notice mood changes, which can also come from pain or living with RA. If it happens, talking to the doctor really helps.

January 20
A myRAteam Member

I had no depression on Humira.

January 14

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