my doctor had told me several years ago that if methotrexate didn't work for me (it does) she would try me on Rinvoq.
December 28, 2025
What are alternatives to methotrexate for rheumatoid arthritis?
If methotrexate isn't working well for you or you're experiencing side effects, there are other disease-modifying antirheumatic drugs (DMARDs) that your doctor might consider. These medications also work to slow RA progression by regulating the immune system.
Show Full Answer
What are alternatives to methotrexate for rheumatoid arthritis?
If methotrexate isn't working well for you or you're experiencing side effects, there are other disease-modifying antirheumatic drugs (DMARDs) that your doctor might consider. These medications also work to slow RA progression by regulating the immune system.
Alternative DMARDs include:
* Hydroxychloroquine (Plaquenil)
* Sulfasalazine (Azulfidine)
* Leflunomide (Arava)
* Azathioprine (Azasan, Imuran)
* Cyclosporine (Neoral, Sandimmune)
Some people use these medications alone, while others combine them with methotrexate for better results. Your rheumatologist can help determine which option might work best for your specific situation.
It's important to discuss any concerns about methotrexate with your doctor before making changes to your treatment plan. They can evaluate your response to the medication and recommend the most appropriate alternative based on your disease activity and overall health.
December 28, 2025
Join
Your Privacy Choices
