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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Cleveland, OH

My Sed Westergren rate is super high and I’m injecting Humira once a week along with taking methotrexate once a week, eight tablets I might add. So now I’m back on a prednisone taper for a short time because I was so sick feeling terrible. And the rheumatologist and I are talking about starting a different medication. This is so exhausting. 😔

September 18, 2025
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A myRAteam Member

I took Humira for about 5 months and didn't have any improvement of my symptoms. My rheumatologist switched me to Enbrel. It took about four months of slow but steady improvement before I felt like myself again.

I hope you can find a biologic that is better for you soon.🤗

September 19, 2025
A myRAteam Member

Humira, I took the generic for it Hydrimoz, did absolutely nothing and my RA went out of control Now on Actemra. We shall see.

September 18, 2025
A myRAteam Member

Humira help my rash and pain but it made me randomly really sick.

September 19, 2025
A myRAteam Member

I have taken a lot of ra medication through out my ra journey and now I'm on on kevsara . Has anyone been on this before . Before that i was on rinvoq

September 19, 2025
myRAteam

It's completely understandable to feel exhausted when treatments aren't working as hoped. Finding the right medication combination can take time, and it's normal for medications to become less effective over time. Working closely with your rheumatologist to adjust your treatment plan is exactly the right approach.

Many Show Full Answer

It's completely understandable to feel exhausted when treatments aren't working as hoped. Finding the right medication combination can take time, and it's normal for medications to become less effective over time. Working closely with your rheumatologist to adjust your treatment plan is exactly the right approach.

Many myRAteam members have shared similar experiences with needing to switch medications. The key is maintaining open communication with your healthcare provider about how you're feeling and any changes in your symptoms. When transitioning between medications, your doctor may need to try different combinations or types of DMARDs to find what works best for your body. Each person responds differently to RA treatments, and it may take some trial and error to find the most effective option for managing your symptoms.

Remember that feeling frustrated during this process is normal, but you're taking the right steps by staying engaged with your treatment plan and working with your rheumatologist to find better solutions.

September 18, 2025

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