Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Hi everyoneDo you experience different things with different makes of methotrxate ?Eg day after - not with it, abit shaky, headaches, etc

A myRAteam Member asked a question 💭
KENT UK

abit shaky/nervy inside .....

April 29, 2024
 · 
Be the first to react
A myRAteam Member

Yes, it is very common for the first couple days after for side effects like nausea, diarrhea, HA, fatigue and brain fog. But high dose folic acid taken 12 hours after the last dose (some people split the dose…me) to reduce severity. Since I have been on it, though, the swelling in my hands hands my feet my knees my body feels so much better and I have really good days. So if I’m in bed one day and relaxing for that day, it is worth it for me.
However, some people just cannot adjust to it. There are many medications and combinations and medication that may work. You need to find the one that works for you.

April 30, 2024
myRAteam

Hello! It's quite common for people to experience varying side effects with methotrexate, depending on factors like the dosage form (injection vs. pills) and individual differences in metabolism and body response. Commonly reported side effects the day after taking methotrexate include:

- Feeling fatigued or mentally Show Full Answer

Hello! It's quite common for people to experience varying side effects with methotrexate, depending on factors like the dosage form (injection vs. pills) and individual differences in metabolism and body response. Commonly reported side effects the day after taking methotrexate include:

- Feeling fatigued or mentally "foggy"
- Headaches
- Shaking or tremors

These symptoms are sometimes referred to as the "methotrexate hangover." If you're finding these side effects particularly challenging, it's important to discuss them with your doctor. They might adjust your dosage or suggest taking the medication at a time that might minimize disruptions to your daily life, such as before the weekend. Additionally, ensuring you're well-hydrated and have eaten can sometimes help mitigate these effects.

April 29, 2024

Related Questions

View All
Beginner's Mind - Not Knowing It All When Living with Rheumatoid Arthritis
Are you living with more than rheumatoid arthritis?
Poll: Members Share Which RA Symptoms Affect Them Most Day to Day