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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 25, 2024
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A myRAteam Member

Jamie, I would try another med for sure. I personally, did horrible on the MTX, both tablets and injections. I can say that I honestly felt worse on that drug. Much better now, thank the good Lord!

March 28, 2024
A myRAteam Member

Thank you for that! It feels like I'm losing my mind (brain fog) and my energy level plummeted. 4 months on mtx now. They want me to try Enbrel....🤔

March 26, 2024
A myRAteam Member

MTX increased my fatigue and brain fog exponentially. After 3 months on it we moved on to something else. It wasn’t worth it for me.

March 26, 2024
A myRAteam Member

I had severe fatigue prior to taking MTX but it was even worse on it. Felt nauseous, had chills, dark circles under my eyes and my nails were brittle. It raised my liver enzymes so I was taken off it and felt so much better. That stuff was harsh

March 25, 2024
A myRAteam Member

Jamie,
I suffered the same with MTX, both in the pill and injection form. I can honestly say that I feel better with no MTX at all. I am now on Leflunomide and Hydroxyquinone and feel much better with less pain and swelling. I hear many folks say that MTX does well for them. I was certainly not one of those. My Rheumy said that I certainly did give it my best try, prob close to 5-6 months, between the pill and injection. I was miserable the entire time, with vomiting, etc.

March 25, 2024

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