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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
STL
January 20, 2022
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Answer Summary

Members shared mixed experiences with Simponi Aria for rheumatoid arthritis, with some reporting significant relief and describing it as... Read more

Members shared mixed experiences with Simponi Aria for rheumatoid arthritis, with some reporting significant relief and describing it as essential to their quality of life, while others found it took several months to work or ultimately stopped being effective over time. Several members noted that combining Simponi with other medications like methotrexate, plaquenil, or sulfasalazine seemed to improve results, though one member mentioned that adding a steroid to the infusion made a noticeable difference and another experienced weight gain as a side effect. A recurring theme was patience and persistence, as doctors often recommend waiting at least six months to fully assess whether the treatment is working, along with warm encouragement and prayers for those just starting their journey.

A myRAteam Member

Yes it has worked for me

January 20, 2022
A myRAteam Member

I was on it for a number of years, the had to change it as it stopped working

January 30, 2022
A myRAteam Member

I'm on Simponi and still waiting for a result after 4 shots (4 months).. My doc says to continue for 6 months.

January 21, 2022
myRAteam

Simponi Aria (Golimumab) is a biologic disease-modifying antirheumatic drug (DMARD) used to treat adults with moderate to severe rheumatoid arthritis. It is administered as an intravenous infusion by a healthcare professional every 8 weeks after initial loading doses.

Key Points
- Mechanism: It works by binding to tumor Show Full Answer

Simponi Aria (Golimumab) is a biologic disease-modifying antirheumatic drug (DMARD) used to treat adults with moderate to severe rheumatoid arthritis. It is administered as an intravenous infusion by a healthcare professional every 8 weeks after initial loading doses.

Key Points:
- Mechanism: It works by binding to tumor necrosis factor alpha (TNF-α), preventing it from signaling the immune system to attack the body’s connective tissues.
- Common Side Effects: Respiratory tract infections, viral infections, elevated liver enzymes, low white blood cell counts, bronchitis, high blood pressure, and rash.
- Serious Side Effects: Severe infections, hepatitis B virus reactivation, increased risk for lymphoma and other cancers, heart failure, nerve damage, lupus-like syndrome, and severe allergic reactions.

For more details, you can visit the [Simponi Aria page on myRAteam](https://www.myrateam.com/treatments/simponi-aria).

July 8, 2024
A myRAteam Member

The infusion I get is Simponi and i don’t think I could make it without it. It works!!!!

January 28, 2022

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