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A myRAteam Member asked a question 💭
Marquette, MI

What if your rheumatoid arthritis progresses on to new, different joints when starting treatment? Does this mean the methotrexate is making your worse? Or would you get worse despite the treatment? I am afraid to take my next dose (8th dose) I am on a high titrated dose of Prednisone after a severe flare where I could barely walk.

October 5, 2020
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Answer Summary

Members rallied around someone worried that methotrexate might be worsening their rheumatoid arthritis as new joints became affected, with the... Read more

Members rallied around someone worried that methotrexate might be worsening their rheumatoid arthritis as new joints became affected, with the overwhelming consensus being that the medication takes significant time to work, typically 6 to 16 weeks or even up to a year, and that progression during this window doesn't mean the treatment is causing harm. Several members shared their own experiences with methotrexate requiring dose adjustments or additional medications like Enbrel, Arava, infliximab, or secukinumab to achieve control, and many cautioned that the high-dose prednisone taper often causes a rebound flare once stopped. A recurring theme was patience with the treatment timeline, staying in close contact with doctors to adjust plans as needed, and trusting that unlike decades past, there are now many more options available if methotrexate alone isn't enough.

A myRAteam Member

Methotrexate & RA progression
Chemotherapy and Immunosuppressive drug. It can be use to treat RA& psoriais steroid agent.It takes a few months to
see if works or not. Please read
its side effects and what to avoid such as alcohol can increase risk of liver damage.This drug works to reduce
inflammation and suppress your immune
system.Remember everyones body is different , may react with diff meds,
or some people may have other
health issue’s I’m no Dr. just get to know
your body even get a second opinion.
Currently no cure for RA, but there are ways to treat it ,slow it down and
suppress your immune system.
Connecting with others living with RA
can provide invaluable support like
this RA team you are part of now.
These are two of my goals
1. How RA affects my life choices
2.What I want family and people to know
Please take care everyone😘
Don’t forget to smile 😃

October 5, 2020
A myRAteam Member

prednisone just for short period of time to get bad RA flare under control.

October 10, 2020
A myRAteam Member

Hello, I am currently on Methotrexate injection 25mg, it stopped working for me. It can take time before the medication works, I was told by my doctor that it can take 6mths to a year for some people to start feeling the effects of the medication. Best thing you can do is consult with your doctor. Hope you feel better soon!

October 5, 2020
A myRAteam Member

Give the meds a chance sometimes they take 6 to 8 week to work. If you continue to have problems contact your Dr. Methotrexate didn't work for me. But we are all a little different. I've had pretty good luck with enbrel and lefonomide ( arava). Prayers for you.

October 8, 2020
A myRAteam Member

They put me on 3 tabs of 20 mg prednisone for three days, then 2 for 3 days and then 1 for 3 days. I'm on my third day and Sooo wired. My rheumatologist just increased my methotrexate. I am now taking 6 tabs of 2.5 mg once a week. I hope it works. I just need to give it a little more time. Thank you.

October 5, 2020

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