Are you on the tablets? I used to hate Tuesdays that was Methotrexate day, I would throw up and by the time the next lot was due I'd just about got my tummy back to normal. I'm happy to say that I have a wonderful doctor and he put me on the injections, noel I have no worries, they go into your tummy, you soon get used to doing them, all I get not is a bit of stinging which soon wears off.I hope this has been helpful to you.

Injectables are the way to go. The pills don't dissolve fast enough and pass through you system too fast. They're a waste.

Hi Julie I used that Methotrexate.

and my girlfriend said it made me an agree person.
So i recorded me on video and low and behold they were right .

Then the doc wanted me to take Methotrexate shots as appose to the tablets

Iza said no way , there has to be a better way , with the pain ( discomfort )
and mood swings and here in I found my story towards help it might not be yours
then again it could hep. Now this combined with Humira that also has side effect
but now a more relaxed dad and boyfriend .

My youngest want to follow in dad footsteps study what makes us tick

Love this .

http://www.bodynmind.kiwi/about_me1.html

ju;ie i was on methotrexate but i got really unwell and it depleted my iron to almost nothing. i am currently on leflunomide but have been off it for nearly 3 months as i've had unavoidable infections. can't wait to get back on it though it works wonderfully and caused my inflammatory markers to dip into the normal range for the 1st time. it also has less side effects than methotrexate

I have wondered the same thing - I am also seronegative but treated with RA drugs -methotrexate, plaquenil, and prednisone!