I take low dose naltrexone 4.5 mg every night. There are absolutely no side effects. I was diagnosed with RA mid 2015. So far it is in my hands only and aside from a couple of bad flares late 2016 not doing too badly. My hands are always sore but manageable. I will keep taking it as I believe it is helpful in so many ways. It costs me 30 dollars a month I had a friend with lung cancer who was sent home to get her affairs in order but heard about it and started taking it and believe it or not her tumours disappeared. She had Ibs as swell and continued smoking crazy woman but lived another seven years. The specialist almost fainted when she walked back into his office a year later. Couldn't believe she was still breathing. If you google it there's tons of information on it. I figure it's worth a try. Good luck.

Yes presently take methotrexate 12.5 mg per week plus folic acid 1 mg. I also take Lots of omega 3 - 2000 mg each DHA and EPA and also alpha lipoic acid and COQ 10 Also curcumin If you ask your compounding pharmacy they probably know which doctors will prescribe Good luck.

Going to a new doctor next week and will ask about it. Saw an ad on TV for a diet medication that contains Naltrexone.

Tried low dose Naltrexone did not work for me. Back on Methotrexate hate it

Oh I think also that since it is already approved in large doses fir opioid dependency that it is already FDA approved but can be prescribed in low doses for what they refer to as off label.