Connect with others who understand.

sign up log in
About myRAteam
Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Ccp Positive To Negative

Ccp Positive To Negative

Curious if it is normal for a high positive CCP to become negative within a month after starting treatment?My RF was negative. I had two weeks of feeling really good and now I feel just as bad as I did before starting treatment. Rheumatologist is looking at Sjogren's also.

A myRAteam Member said:

My anti ccp was a strong positive 3 years ago when I was diagnosed. My rheumatologist said they don't usually redraw them. She wants me in a research program for a rituxan biosimilar. My anti ccp was redrawn in Feb but came back negative. I've been on methotrexate, Plaquenil, and Humira together for at least 2 years. I didn't qualify for the study because of the Anti ccp. My RF has always been negative. I still have active disease with new erosions in my hands. I'm off everything right now to try to qualify again in June. It sucks being off everything just to try a research drug. I'm on LTD from my job and can't afford the copays AND Cobra. I found your question looking specifically for this same question. I have found literature that says the anti ccp decreases with treatment. I'm not sure with it going to negative why there is still active disease going on still. I just know it's frustrating...everything about this disease is!

posted over 3 years ago
A myRAteam Member said:

Hmmm scans show no inflammation? I wouldnt stick with that. If you can get a second opinion. It took me 5 years to get someone who had a clue. Not trying to be insulting i can only imagine how hard is for doctors to to figure out what can cause autoimmune issues. I hope you get answers soon and the treatment you need. I find that when i stick with turmeric supplements that have the pineaple enzyme or black pepper (for absortion) i feel way better. Also bromelain supplements highest strength helps me so much to. They dont have any issues with our meds. My rheum actually encourages me to take whatever supplement i want. Lots of hugs quality of life is crappy i am sure with what you are goiing through

posted over 3 years ago
A myRAteam Member said:

I had a joint scan done at Mayo and it did not show any damage. Doc is pretty sure I have Sjogrens and RA and possibly fibro

posted over 3 years ago
A myRAteam Member said:

Oh gosh it sounds like your pain is constant? I am so sorry. Have you had any CT scans of your affected joints (hands, feet, back etc) cause that at was the only way i was able to be diagnosed with RA. Doctors went back and forth between fybromyalgia, lupus, and idiopathic urticaria. Treatments i was told dont start helping until sometimes 2 to 3 months later.

posted over 3 years ago
A myRAteam Member said:

Thanks. Treatment isn't really helping me either at this point. Started neurontin to help with sleep and some pain.

posted over 3 years ago
Browse more questions and answers
Continue with Facebook
Sign up with your email
Already a Member? Log in