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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

How Do You Feel On Shot Day After Your Shot?

A myRAteam Member asked a question 💭
Shillington, PA

How do you feel after your shot? Do you feel tired? Do you feel something different in your body? I took my first Enbrel shot today. Not sure how I feel.

March 26, 2015 (edited)
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Answer Summary

Members shared mixed experiences with Enbrel for rheumatoid arthritis, with some finding it highly effective while others saw no improvement... Read more

Members shared mixed experiences with Enbrel for rheumatoid arthritis, with some finding it highly effective while others saw no improvement or experienced side effects like varicose veins at injection sites, increased infections, or oral lichen planus from a weakened immune system. Several members described common post-injection symptoms including fatigue the day after their shot, nausea, injection site tenderness, and one member noting severe nausea that made car travel impossible on shot day. A recurring theme was the patience required when starting biologics, as some can take up to six months to work, and the importance of working closely with doctors to find the right medication, with one member sharing success after switching to Xeljanz following complications.

A myRAteam Member

I'm a big fan. It was very effective for me. However, you have to watch your infection levels - I finally got to a place where I couldn't take it anymore. It was very effective when I took it.

March 31, 2015
A myRAteam Member

I felt fine. Have been on Enbrel for about 5 years. Due to a weakened immune system, I have had some unpleasant side effects such as oral lichen planus

March 30, 2017
A myRAteam Member

I am on my 3rd injection as of yesterday ...I am extremely tired the next day

August 15, 2015
A myRAteam Member

I get very tired then nauseous the next morning. I cannot travel in a vehicle or I vomit the evening of my shot

July 6, 2015
A myRAteam Member

@A myRAteam Member it's good to hear you found meds that work. It always seems when I find something that starts to work the side affects always seem to be worse... Just gotta take it one day at a time.

April 9, 2015

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