Taking prednisone while on Xeljanz (tofacitinib) is something many people with RA do, but it's important to understand the potential risks and always consult your rheumatologist before combining them. Both medications suppress the immune system, so combining them could increase the risk of serious infections. Here are some Show Full Answer
Taking prednisone while on Xeljanz (tofacitinib) is something many people with RA do, but it's important to understand the potential risks and always consult your rheumatologist before combining them. Both medications suppress the immune system, so combining them could increase the risk of serious infections. Here are some key things to be aware of:
- Infections: Both Xeljanz and prednisone suppress the immune system. Using them together may raise the risk of serious infections.
- Stomach and intestinal damage: Both drugs list this as a potential side effect, so the risk may be higher when combined.
- Bone density: Long-term prednisone use can lead to reduced bone density, especially without calcium and vitamin D supplementation.
- Blood sugar and blood pressure: Prednisone can affect both, so monitoring is important. Prednisone is often used short-term to manage flares or bridge gaps in treatment, so it's not unusual for a rheumatologist to prescribe it alongside Xeljanz. The key is using the lowest effective dose for the shortest time possible.
Always check with your rheumatologist before making any changes to your medications.
October 21
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