Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Rinvoq is losing its effectiveness and enbrel didn't help at all.

1 day ago
 · 
Reactions
myRAteam

That's a really specific and important question! Unfortunately, there aren't any myRAteam member experiences available here regarding alpha-gal allergy and biologic choices to share directly.

What is known is that since Rinvoq (upadacitinib) is losing effectiveness and Enbrel (etanercept) didn't work, there are still Show Full Answer

That's a really specific and important question! Unfortunately, there aren't any myRAteam member experiences available here regarding alpha-gal allergy and biologic choices to share directly.

What is known is that since Rinvoq (upadacitinib) is losing effectiveness and Enbrel (etanercept) didn't work, there are still several other options worth discussing with your rheumatologist. There are several classes of biologics and targeted treatments approved for RA that work differently from Enbrel and Rinvoq:

- B-cell inhibitors – such as Rituxan (rituximab), given by infusion
- Interleukin inhibitors – such as Actemra (tocilizumab) or Kineret (anakinra)
- Selective costimulation modulators – such as Orencia (abatacept), available as injection or infusion
- Other JAK inhibitors – such as Olumiant (baricitinib) or Xeljanz (tofacitinib)
- Other TNF inhibitors – such as Humira (adalimumab) or Cimzia (certolizumab pegol)

Bringing up the alpha-gal allergy specifically with your rheumatologist is really important, as it may influence which biologics are safest for you. They can review ingredients and delivery components carefully before prescribing.

1 day ago

Related Questions

View All
A myRAteam Member asked a question 💭

Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data and Privacy policies.
Already a member? Log In