That's a really specific and important question! Unfortunately, there aren't any myRAteam member experiences available here regarding alpha-gal allergy and biologic choices to share directly.
What is known is that since Rinvoq (upadacitinib) is losing effectiveness and Enbrel (etanercept) didn't work, there are still Show Full Answer
That's a really specific and important question! Unfortunately, there aren't any myRAteam member experiences available here regarding alpha-gal allergy and biologic choices to share directly.
What is known is that since Rinvoq (upadacitinib) is losing effectiveness and Enbrel (etanercept) didn't work, there are still several other options worth discussing with your rheumatologist. There are several classes of biologics and targeted treatments approved for RA that work differently from Enbrel and Rinvoq:
- B-cell inhibitors – such as Rituxan (rituximab), given by infusion
- Interleukin inhibitors – such as Actemra (tocilizumab) or Kineret (anakinra)
- Selective costimulation modulators – such as Orencia (abatacept), available as injection or infusion
- Other JAK inhibitors – such as Olumiant (baricitinib) or Xeljanz (tofacitinib)
- Other TNF inhibitors – such as Humira (adalimumab) or Cimzia (certolizumab pegol)
Bringing up the alpha-gal allergy specifically with your rheumatologist is really important, as it may influence which biologics are safest for you. They can review ingredients and delivery components carefully before prescribing.
1 day ago