Yes, RA can absolutely cause flu-like symptoms and fatigue — and you're far from alone in experiencing this. In fact, studies show that people with RA experience fatigue levels four to eight times higher than those without the condition.
During a flare-up, many people report symptoms that feel very similar to having the Show Full Answer
Yes, RA can absolutely cause flu-like symptoms and fatigue — and you're far from alone in experiencing this. In fact, studies show that people with RA experience fatigue levels four to eight times higher than those without the condition.
During a flare-up, many people report symptoms that feel very similar to having the flu, including:
- Low-grade fever (between 99–101°F)
- Extreme tiredness and fatigue
- Appetite loss
- Deep, aching joint pain and stiffness
- A general feeling of being unwell As one myRAteam member described it, a flare can feel like "the deep-down bone ache, the never-ending exhaustion, and fever." Another said it feels like "getting run over by a truck that's on fire."
The main reason for these symptoms is inflammation. When RA is active, the immune system is in overdrive, which can trigger that run-down, flu-like feeling throughout the whole body — not just in the joints. Fatigue in particular can be one of the most frustrating parts of living with RA. It's not just ordinary tiredness — it can affect mood, focus, and the ability to get through daily tasks.
Some things that can make RA fatigue worse include:
- Active inflammation
- Poor sleep
- Joint pain
- Stress and anxiety
It's worth bringing both fatigue and any flu-like symptoms up with a rheumatologist, as they can help adjust treatment to better manage these symptoms.
July 29
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