I Am on methotrexate 25 mg inj and I'm doing ok as the tablets made me so ill I do have some off days where I feel a bit sick and out of sorts and I find as it's becoming due I feel
A bit rubbish but better than the tablets by far
July 27
Just be careful using methotrexate. I was on it a couple of years and ended up in the hospital for a week. It affected my lungs.
July 21
Congrats on taking that first step — literally! Starting methotrexate (MTX) is a big milestone in managing RA. Many people on myRAteam have shared their experiences, and it's helpful to know what to expect.
Here's what's commonly reported:
- It takes time to work — most people start noticing improvement between 3 to 6 Show Full Answer
Congrats on taking that first step — literally! Starting methotrexate (MTX) is a big milestone in managing RA. Many people on myRAteam have shared their experiences, and it's helpful to know what to expect.
Here's what's commonly reported:
- It takes time to work — most people start noticing improvement between 3 to 6 weeks, with continued improvement over 3 months
- Early side effects are common — nausea, fatigue, and digestive issues are the most frequently reported
- "Methotrexate fog" — some people feel fatigued or mentally foggy the day after their dose
- Things often improve — many find side effects ease up after the first few months One myRAteam member shared that after about six months, the day-after fatigue they initially experienced completely went away. Another said after three months they had hardly any flares and felt more like themselves again.
A few tips that may help along the way:
- Take folic acid daily — it helps reduce mouth sores and digestive side effects
- Split your dose — taking half in the morning and half at night (no more than 12 hours apart) can ease nausea
- Stay in touch with your doctor — routine blood tests will monitor your liver and overall health
Always keep your rheumatologist informed of any changes you notice! 💪
July 20
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