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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Rockbridge, OH
July 13
 · 
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A myRAteam Member

Yes it does unfortunately cause irritability my family & friends noticed it with me

July 13
A myRAteam Member

Oh dear Lord YES!!! Its a steroid and you've probably heard of "Roid Rage"??? If not, Google it!

July 15
A myRAteam Member

Yes! It makes me so anxious and even depressed.

July 15
myRAteam

Yes, prednisone can cause irritability. It's a corticosteroid commonly used to manage RA inflammation, but it comes with a range of side effects that can affect mood and sleep — and a grumpy, sleep-deprived person is rarely a happy one!

Prednisone is known to interfere with sleep, which can lead to:

- Fatigue
- Show Full Answer

Yes, prednisone can cause irritability. It's a corticosteroid commonly used to manage RA inflammation, but it comes with a range of side effects that can affect mood and sleep — and a grumpy, sleep-deprived person is rarely a happy one!

Prednisone is known to interfere with sleep, which can lead to:

- Fatigue
- Forgetfulness
- Irritability during waking hours

As one myRAteam member put it, "I have a love/hate relationship with prednisone. Nothing on earth can compare with it for wiping out pain from a flare, but the severe insomnia is unbearable." To help reduce sleep disruption from prednisone, try taking it early in the morning rather than later in the day. This is a simple but effective way to lessen its impact on your sleep cycle.

It's always worth discussing mood and sleep concerns with your rheumatologist, as they may be able to adjust your dosage or suggest strategies to manage these side effects.

July 13
A myRAteam Member

Thank you! Unfortunately, that explains that explains much.

July 19

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