Yes, developing rheumatoid nodules can be a sign that RA is progressing. They are considered an "extra-articular" feature of RA, meaning inflammation has spread beyond the joints to other parts of the body.
Nodules are firm, flesh-colored lumps that form just under the skin, typically in areas of repeated pressure. They Show Full Answer
Yes, developing rheumatoid nodules can be a sign that RA is progressing. They are considered an "extra-articular" feature of RA, meaning inflammation has spread beyond the joints to other parts of the body.
Nodules are firm, flesh-colored lumps that form just under the skin, typically in areas of repeated pressure. They commonly appear on the:
- Fingers
- Elbows
- Forearms
- Heels
- Lower back (sacrum)
- Hips Between 25% and 40% of people with RA develop nodules, most often those who test positive for rheumatoid factor (RF) or anti-CCP antibodies. Smokers and those with more severe RA also have a higher risk.
It's worth noting that methotrexate can sometimes trigger rapid nodule growth, known as accelerated nodulosis. A myRAteam member shared that after noticing their nodules growing, testing confirmed it was linked to methotrexate — and once they stopped taking it, the nodules began to go away.
⚠️ Never stop any RA medication without consulting your rheumatologist first, as this could affect your health outcomes.
If you notice any new lumps, it's a good idea to schedule an appointment with your doctor soon.
July 3
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