Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is flatulence and watery diarhea a side effect of Methotexrate?

A myRAteam Member asked a question 💭
Devon, UK
June 17
 · 
Reactions
myRAteam

Great question! Gastrointestinal (GI) issues are actually among the most common side effects of methotrexate, affecting anywhere from 20% to 65% of people with RA who take it.

Common GI-related side effects include:

- Nausea
- Vomiting
- Diarrhea
- Stomach pain

While flatulence isn't specifically listed as a named side effect Show Full Answer

Great question! Gastrointestinal (GI) issues are actually among the most common side effects of methotrexate, affecting anywhere from 20% to 65% of people with RA who take it.

Common GI-related side effects include:

- Nausea
- Vomiting
- Diarrhea
- Stomach pain

While flatulence isn't specifically listed as a named side effect, it can be part of the broader GI upset that methotrexate can cause. Watery diarrhea falls under the diarrhea category, so that one is definitely on the list. It's always a good idea to let your rheumatologist know if these symptoms are bothering you. They may be able to adjust your dose or suggest ways to manage the discomfort. Some people find that symptoms improve over time as their body adjusts to the medication.

June 17
A myRAteam Member

Yes, Unfortunately I did experience the same thing while on it. It did get better, but I never truly felt good while my RA symptoms were better. Not feeling good 4 days per week wasn't worth staying on it.

June 17

Related Questions

View All
Tingling and Numbness: Is It a Side Effect of Methotrexate for RA?
Do Biologics Cause Weight Gain? Body Changes and Side Effects
Can Leg Cramps Be a Side Effect of Methotrexate for RA?
Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data and Privacy policies.
Already a member? Log In