Rituxan (rituximab) works by targeting specialized immune cells called B cells. In RA, B cells produce harmful autoantibodies that mistakenly attack healthy joint tissue, causing inflammation and damage. Rituxan essentially eliminates these B cells so they can no longer produce those damaging autoantibodies.
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Rituxan (rituximab) works by targeting specialized immune cells called B cells. In RA, B cells produce harmful autoantibodies that mistakenly attack healthy joint tissue, causing inflammation and damage. Rituxan essentially eliminates these B cells so they can no longer produce those damaging autoantibodies.
Think of it like removing the troublemakers from the party — once the B cells are gone, the immune system can't use them to attack your joints. Here's what to expect with Rituxan treatment:
- The first course is typically two infusions, given two weeks apart
- A corticosteroid is given by IV about 30 minutes before each infusion to help reduce side effects
- Each infusion takes roughly 3 to 4 hours
- Improvements may not be noticeable until 3 months or more after treatment
- Once it works, benefits can last 6 to 12 months or longer
- Your rheumatologist may recommend repeating treatment every 6 months
It's worth noting that Rituxan is generally prescribed when other RA treatments haven't worked well enough. As with any RA medication, there are potential risks to be aware of, including an increased chance of infections like upper respiratory or skin infections. There is also a small risk of reactivating dormant viral infections, so screening is typically done before starting treatment.
Always discuss any concerns with your rheumatologist to make sure it's the right fit for you.
June 14
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