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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Kissimmee, FL

Seronegative RA

May 11
 · 
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How To Avoid Dangerous Interactions With RA Medications Read Article...
myRAteam

Great question! Topical treatments like diclofenac (sold as Voltaren gel) can be a helpful addition to managing seronegative RA pain. They work by delivering anti-inflammatory relief directly to the affected joint without affecting the whole body the way oral medications do.

This makes them appealing for people who Show Full Answer

Great question! Topical treatments like diclofenac (sold as Voltaren gel) can be a helpful addition to managing seronegative RA pain. They work by delivering anti-inflammatory relief directly to the affected joint without affecting the whole body the way oral medications do.

This makes them appealing for people who experience side effects from systemic RA medications, or who want extra relief on top of their current treatment plan. A myRAteam member shared that Voltaren gel is "the best topical I've found" — though they did note it has a bit of a smell. Another said the over-the-counter extra strength version "really helps."

It's worth knowing that topicals like diclofenac:

- Provide short-term pain relief only
- Do not treat the underlying cause of RA or slow joint damage
- Can be used alongside your regular RA medications
- Are available over the counter or by prescription

Since you have seronegative RA, your rheumatologist is the best person to advise on how topicals fit into your overall treatment plan, especially if you're already on DMARDs, biologics, or other medications. Always check with them before adding something new to avoid any unexpected interactions.

May 11

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