Does biological treatment work when methotrexate isn't helping enough?
Yes, biologic drugs can be very effective for rheumatoid arthritis, especially when methotrexate alone isn't providing adequate relief. Biologics are often prescribed when traditional DMARDs like methotrexate haven't controlled symptoms well enough.
Show Full Answer
Does biological treatment work when methotrexate isn't helping enough?
Yes, biologic drugs can be very effective for rheumatoid arthritis, especially when methotrexate alone isn't providing adequate relief. Biologics are often prescribed when traditional DMARDs like methotrexate haven't controlled symptoms well enough.
Biologics work differently than methotrexate. They target specific overactive proteins in your immune system that cause inflammation in joints. This targeted approach can mean fewer side effects and better results for many people.
What to expect with biologics:
- They often take a few weeks to months to start working, though some people feel better after their first treatment
- They're frequently used in combination with methotrexate for better results
- Common biologics include Humira, Enbrel, Remicade, and Cimzia
- They're given by injection or infusion since they can't be taken as pills
A myRAteam member shared: "I'm on a biologic, infused every six weeks, and personally, it's been a miracle. I'm now in remission and feel so blessed to feel like my old self!"
Before starting a biologic, you'll need screening tests for infections like tuberculosis and hepatitis, since biologics suppress parts of your immune system.
Talk with your rheumatologist about whether biologics might be right for you.
March 5