Is it common to feel extra sore the day after taking methotrexate?
Feeling extra sore the day after taking methotrexate isn't typically listed as a direct side effect. However, some people experience what's called "methotrexate fog" - a feeling of fatigue, headaches, mental fog, and difficulty concentrating that can occur Show Full Answer
Is it common to feel extra sore the day after taking methotrexate?
Feeling extra sore the day after taking methotrexate isn't typically listed as a direct side effect. However, some people experience what's called "methotrexate fog" - a feeling of fatigue, headaches, mental fog, and difficulty concentrating that can occur the day after taking a dose.
Since you're newly diagnosed and only on your third dose, it's important to know that methotrexate takes time to work - usually several weeks to months. During this adjustment period, your RA symptoms may still be active, which could explain the soreness you're experiencing.
The timing of feeling worse after taking your dose might be coincidental rather than directly caused by the medication. Many people initially think they feel worse after taking methotrexate, but this often improves after several months as the medication builds up in your system and starts working more effectively. It's definitely worth mentioning this pattern to your rheumatologist. They can help determine if what you're experiencing is related to the medication or your RA symptoms, and they may be able to adjust your treatment plan if needed. Don't stop taking your medication without talking to your doctor first.
Keep track of when the soreness happens and how long it lasts - this information will be helpful for your healthcare team.
February 19
Join
Your Privacy Choices
