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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
February 11
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A myRAteam Member

Thank you so much! That is very encouraging!

February 13
A myRAteam Member

I think it's a great drug. I have had absolutely no side effects from it!

February 13
myRAteam

What are your thoughts on starting hydroxychloroquine after stopping methotrexate?

Switching from methotrexate to hydroxychloroquine is a decision your doctor likely made based on your specific situation. It's important to understand why this change might help you.

Stopping methotrexate without a replacement medication Show Full Answer

What are your thoughts on starting hydroxychloroquine after stopping methotrexate?

Switching from methotrexate to hydroxychloroquine is a decision your doctor likely made based on your specific situation. It's important to understand why this change might help you.

Stopping methotrexate without a replacement medication can be risky. About half of people who stop their DMARDs experience flare-ups within six months. Starting hydroxychloroquine before completely stopping methotrexate might help prevent a flare-up during the transition.

Here are some things to discuss with your rheumatologist:

• Why hydroxychloroquine is being recommended for you specifically
• Whether you should start it before fully stopping methotrexate
• How long it typically takes to feel the effects
• What side effects to watch for
• What to do if you experience a flare-up during the transition

Some myRAteam members have shared experiences with hydroxychloroquine, noting differences in side effects between name-brand Plaquenil and generic versions. If you experience stomach upset or other side effects, let your doctor know.

The most important thing is to stay in close communication with your rheumatologist throughout this medication change. They can monitor how you're responding and adjust your treatment plan if needed.

February 11

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Montreal, QC