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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I've developed red flaky skin around both eyes and a patch on my forehead. Is this RA related or a side effect from taking methotrexate?

A myRAteam Member asked a question 💭
Safford, AZ
February 9
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Reactions
A myRAteam Member

I agree 109% to yiur post

Get to a dermatologist

Knowledge is puert. Get ahead of everything yiu are yiur own advocate.
Clarice Burke

February 11
A myRAteam Member

So I’ve had RA over 10 years. I had been on Methotrexate on and off for a long period of the time. Been on Humira and now on Leflumide. I see a dermatologist every 6 months now. Some of the patches of dry skin turned out to be skin cancer on my face. I had two surgeries on squamous cell carcinoma and one on Basal cell carcinoma. N several froze off. I suggest all RA people to go see a dermatologist. I’m not sure if it is from meds or not but it’s my suggestion. Dry rough skin that doesn’t go away or a pimple/bump or of course moles go see a dermatologist.

February 11
A myRAteam Member

Sometimes we don’t take good care of those areas that are very delicate areas. It has been such cold weather so our ski. Needs to be protected My answer is ask the rheumatologist or a dermatologist. I don’t play when is it by my eyes 🩷👍🧸

February 9
A myRAteam Member

Serious Skin Reactions: Blistering, peeling, or a rash that spreads is definitely a side effect of Methotrexate? My suggestion to contact a dermatologist or yiur permits or OCT. my Amazon is it spreading?
Is it spreading?

February 9
myRAteam

Is red, flaky skin around your eyes and forehead related to RA or a side effect of methotrexate?

Red, flaky skin could potentially be a side effect of methotrexate. While itchy or discolored skin is listed as a common side effect, methotrexate can also cause serious skin reactions in some people.

It's important to contact Show Full Answer

Is red, flaky skin around your eyes and forehead related to RA or a side effect of methotrexate?

Red, flaky skin could potentially be a side effect of methotrexate. While itchy or discolored skin is listed as a common side effect, methotrexate can also cause serious skin reactions in some people.

It's important to contact your doctor right away if you notice any skin changes while taking methotrexate, especially:

* Peeling skin
* Blisters
* Rash
* Skin discoloration or pinpoint red spots

Your rheumatologist needs to evaluate whether this is a medication side effect or related to your RA. They can determine the cause and recommend appropriate treatment without compromising your RA management.

Don't wait to reach out — skin reactions from methotrexate can sometimes be serious and require prompt medical attention.

February 9

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