What concerns do you have about taking Xeljanz?
It's completely understandable to feel worried about starting a new medication. Xeljanz (tofacitinib) is a JAK inhibitor that's prescribed for people who haven't responded well to or can't tolerate methotrexate. It works by blocking specific signaling proteins that contribute Show Full Answer
What concerns do you have about taking Xeljanz?
It's completely understandable to feel worried about starting a new medication. Xeljanz (tofacitinib) is a JAK inhibitor that's prescribed for people who haven't responded well to or can't tolerate methotrexate. It works by blocking specific signaling proteins that contribute to inflammation.
Like all RA medications, Xeljanz does come with potential risks. These can include:
* Upper respiratory infections
* Headaches
* Gastrointestinal issues
* Increased risk of serious infections
* Blood clots
* Certain cancers
* Heart problems
The specific risks can vary based on your overall health and medical history, which is why having an open conversation with your rheumatologist is so important. They can help you weigh the benefits against the risks for your particular situation.
You might also want to ask your doctor how long Xeljanz has been available and what newer data shows about its long-term safety. Early reports of side effects often reflect experiences from people with more severe disease, and as medications are used more widely, the average risk profile can become clearer.
Many myRAteam members have shared their experiences with various RA treatments, and you're not alone in having concerns about starting something new.
February 3
I would also like to hear of people’s experience's with JAK inhibitor's. I know the side effects and risks. If orencia fails , this is the next recommendation for me as well.
February 3
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