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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
January 23
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myRAteam

Is intense itching in your legs related to RA?

Yes, itching can be related to rheumatoid arthritis, though it's not a classic symptom. Many myRAteam members report experiencing intense itching, with some describing it as unbearable or feeling like something is crawling on their skin.

There are several possible RA-related Show Full Answer

Is intense itching in your legs related to RA?

Yes, itching can be related to rheumatoid arthritis, though it's not a classic symptom. Many myRAteam members report experiencing intense itching, with some describing it as unbearable or feeling like something is crawling on their skin.

There are several possible RA-related causes for your leg itching:

RA medications are a common culprit. Disease-modifying antirheumatic drugs (DMARDs) like methotrexate, biologics, and JAK inhibitors can all cause itching as a side effect. One myRAteam member shared experiencing unbearable itching on their hands and feet after starting medication.

RA inflammation itself can trigger itching. Some members notice itchiness around joints when swelling occurs. Research shows that inflammatory autoimmune conditions like RA are associated with chronic hives, which are typically very itchy.

RA complications like rheumatoid vasculitis (inflammation of blood vessels) or kidney disease can also cause itching. About 25 percent of people with RA develop kidney disease, which is known to cause itching.

Dry skin is another factor, as research has found that people with RA may have drier skin than others, which can affect any part of the body including the legs.

It's important to talk to your doctor about your itching. They can help determine the specific cause and recommend appropriate treatment, especially if it might be medication-related or signal a complication.

January 23

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