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A myRAteam Subscriber asked a question 💭
January 23
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Do the same rules apply to Benepali (etanercept)?

Yes, Benepali is a biosimilar version of etanercept (Enbrel), so the same guidelines and precautions apply. This includes how you take it, potential side effects, and safety considerations.

Administration
Benepali is given as a subcutaneous injection, typically in the Show Full Answer

Do the same rules apply to Benepali (etanercept)?

Yes, Benepali is a biosimilar version of etanercept (Enbrel), so the same guidelines and precautions apply. This includes how you take it, potential side effects, and safety considerations.

Administration:
Benepali is given as a subcutaneous injection, typically in the thigh or abdomen. You can give it to yourself at home or have someone help you. It's important to rotate injection sites each time to avoid skin reactions.

Important precautions include:

- Screening for infections (tuberculosis, hepatitis B and C, HIV, varicella-zoster) before starting
- Avoiding live vaccines while on treatment
- Annual skin exams due to increased risk of nonmelanoma skin cancers
- Monitoring for signs of infection, including fever
- Discussing pregnancy or breastfeeding plans with your doctor

Potential side effects:

- Increased infection risk
- Possible weight gain (average around 5 pounds)
- Injection site reactions
- Skin conditions like eczema flares in some people

If you experience bothersome side effects or have concerns about your treatment, talk with your rheumatologist about your options.

January 23

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