What RA treatments are commonly used and what side effects do they cause?
Many people with RA take disease-modifying antirheumatic drugs (DMARDs) like methotrexate, leflunomide, hydroxychloroquine, or sulfasalazine. These medications work slowly to treat the root cause of the disease, typically taking one to three months Show Full Answer
What RA treatments are commonly used and what side effects do they cause?
Many people with RA take disease-modifying antirheumatic drugs (DMARDs) like methotrexate, leflunomide, hydroxychloroquine, or sulfasalazine. These medications work slowly to treat the root cause of the disease, typically taking one to three months to show effects.
Common side effects of conventional DMARDs include:
* Gastrointestinal problems
* Hair loss
* Fatigue
* Nerve damage
* Liver problems
* Increased risk of infection
Some side effects can be reduced by taking supplements like folic acid alongside your medication. Regular blood tests are important to monitor liver function and blood count.
A myRAteam member shared their experience: "Started methotrexate and not tolerating it." Another member mentioned: "I take methotrexate once a week...today is the dreaded day."
Biologic DMARDs like Humira (adalimumab) are also commonly prescribed. These can cause upper respiratory infections, headaches, and gastrointestinal issues. Rare but serious risks include increased chance of infections, blood clots, certain cancers, and heart problems.
For immediate pain relief, doctors often prescribe NSAIDs or corticosteroids while waiting for DMARDs to take effect. NSAIDs can cause stomach irritation or ulcers, while corticosteroids are typically used short-term during flares.
If side effects become unmanageable, talk with your rheumatologist about adjusting your treatment plan.
January 21