I'm with you. All medications come with side effects and unfortunately, most RA meds have similar or identical side effects. If they are overwhelming to the point of not being able to function, then it is definitely time to change things. Otherwise, just keep your doctor informed about your side effects. Keep a journal about when you feel the most affected -- right after infusion, days later, the day before your next scheduled treatment, etc. This can help narrow down the what/when/why of the fatigue. Also, be sure to let the doctor know if anything seems to make things better or if there things that make things worse. Keep track of how long it makes you feel miserable. Then you can provide your doctor with detailed information and can decide what next steps are. Good luck with all of it!!!

Some of that fatigue and feeling sleepy can actually cause some feelings of depression. I had already been dealing with depression when I began remicade, so I don't know if it contributed to anything or not.
Unfortunately, it also caused drug-induced Lupus in me. They had me see a neuropsychologist who said in a report that I needed "biblio" therapy in the form of the book called, "Stop Being Your Symptoms, Start Being Yourself." Yep. It was all in my head. So they sent me three hours away because I insisted that there was something wrong. The doctor I saw was LIVID. He said he was getting tired of getting sent all my doctor's patients because he couldn't figure things out. ONE blood test done months before at my home clinic could have told them what was wrong -- drug-induced Lupus. It was NOT all in my head. I immediately stopped and within two months I was finally not stumbling or dropping things or forgetting everything, etc. So frustrating.

I hope your symptoms go away soon and that you can start living your life as normal. Good luck!

I was pretty tired after starting Remicade, too. MD suggested I give it 6 months before deciding whether or not to continue. At about the 4th month, I started to feel better. I surely wouldn't change doctors, but suggest you let your MD know. Good luck -- treatment is all trial and error in my 40+ plus years experience living wth RA.

Pamela, I was diagnosed just before Christmas with a rare reaction to a drug. Drug induced vasculitis. Rheumatologist had prescribed Taltz and after 2nd injection, a severe blood clotting rash broke out on both feet crippling me through entire holiday period. Still recovering and my feet will be scarred for life.
She is also responsible for dismissing "rashes" which turned out to be rapidly spreading and infected inverse psoriasis.

It is nothing short of negligence for a doctor to not take a patient's concerns and symptoms seriously.
I see my rheumatologist on Wednesday to discuss all this fallout.

I'm sorry you've had to deal with a similar problem. I agree with Bea. Change doctors.