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January 12
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myRAteam

Are Simponi injections effective for rheumatoid arthritis when taken once a month?

Simponi (golimumab) is a biologic medication used to treat rheumatoid arthritis. It's a TNF inhibitor, similar to other biologics like Humira and Enbrel, which work by targeting specific proteins in the immune system that cause inflammation Show Full Answer

Are Simponi injections effective for rheumatoid arthritis when taken once a month?

Simponi (golimumab) is a biologic medication used to treat rheumatoid arthritis. It's a TNF inhibitor, similar to other biologics like Humira and Enbrel, which work by targeting specific proteins in the immune system that cause inflammation and joint damage.

Simponi is typically given as a subcutaneous injection once a month. Like other biologics, it can take time to start working - many people don't see significant improvement for several weeks to a few months after starting treatment.

The effectiveness of Simponi varies from person to person. Some people experience significant relief from their RA symptoms, while others may not respond as well. It's often used when other treatments haven't provided adequate relief.

Common considerations with Simponi include:

- It may be used alone or combined with other DMARDs like methotrexate
- Injection site reactions (redness, swelling, or pain) can occur
- Like all biologics, it can increase infection risk since it affects the immune system
- Regular monitoring by your rheumatologist is important

If you're considering Simponi or have questions about how it's working for you, discussing your specific situation with your rheumatologist can help determine if it's the right choice or if adjustments are needed.

January 12
A myRAteam Member

I don't think the once a month simponi injection is any good. My RA pain has got a lot worse since I've been on it.

January 16
A myRAteam Member

I am not taking anything with it. Pretty much everything I tried before Simponi made me sick to the point where I couldn’t even function. I have an appointment with my rheumatologist and we are going to look at other options

January 12
A myRAteam Member

It worked for me, about a year, then suddenly it didn't.
Are you taking another RA med with it?
It originally was not meant to be a stand alone med.

January 12

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