I take methotrexate and other meds because I also got Sarcoidosis that can cause my arthritis worse.
December 29, 2025
Are you concerned about hair loss while starting methotrexate?
It's completely understandable to feel nervous about this. The good news is that hair loss from methotrexate is less common than you might think, affecting about 1-3% of people, though some studies show rates up to 9%. When it does happen, it's usually mild and Show Full Answer
Are you concerned about hair loss while starting methotrexate?
It's completely understandable to feel nervous about this. The good news is that hair loss from methotrexate is less common than you might think, affecting about 1-3% of people, though some studies show rates up to 9%. When it does happen, it's usually mild and often improves if the medication is stopped.
Your rheumatologist prescribing folic acid is a smart move. While folic acid may not completely prevent hair loss, it helps reduce other common side effects like nausea and mouth sores. Taking it as prescribed is important for managing potential side effects.
What to watch for:
If you notice large clumps of hair falling out during washing or combing, or develop patchy or sudden hair loss, contact your healthcare provider right away. These aren't typical and need attention.
Managing your concerns:
Remember that methotrexate is one of the most effective treatments for slowing RA progression and protecting your joints from damage. The benefits often outweigh the risks, but it's worth discussing your specific concerns with your rheumatologist. They can adjust your dosage or explore other options if needed.
Many people take methotrexate successfully without significant hair issues, and your doctor will monitor you closely.
December 28, 2025