Is it possible to stop hydroxychloroquine when inflammation levels are low?
Yes, this is possible. If you're in remission from RA with dramatically improved symptoms and low inflammation levels, your doctor may give you the option of stopping hydroxychloroquine or reducing your dose.
Some guidelines recommend slowly Show Full Answer
Is it possible to stop hydroxychloroquine when inflammation levels are low?
Yes, this is possible. If you're in remission from RA with dramatically improved symptoms and low inflammation levels, your doctor may give you the option of stopping hydroxychloroquine or reducing your dose.
Some guidelines recommend slowly tapering off medication if RA is well controlled. Before making any changes, your rheumatologist will consider several factors:
• Whether you experience side effects from the medication
• How long you've been in remission
• Your concerns about experiencing a disease flare-up if you lower your dose
Your rheumatologist may be okay with you stopping hydroxychloroquine altogether, changing your dosage, or taking it less frequently to help prevent flare-ups and keep you in remission. What if symptoms return after stopping?
If you experience a flare-up after stopping or reducing hydroxychloroquine, your RA may become active again. In that case, your healthcare provider may suggest going back on your previous treatment plan.
Some people who stop taking anti-malarial drugs abruptly may have a higher risk for a disease flare, though individual risk depends on many factors. Your doctor can help you understand your specific situation.
Never stop or change your medication without talking to your doctor first. They can guide you on whether it's safer to taper off your dosage and provide the best approach for your situation.
December 8, 2025
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