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A myRAteam Member asked a question 💭
Mercersburg, PA
November 25, 2025
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What would you like to know about leflunomide?

Leflunomide, sold under the brand name Arava, is a disease-modifying antirheumatic drug (DMARD) used to treat rheumatoid arthritis. It works by targeting the immune system to reduce inflammation and slow down the progression of RA.

Here are some key points about leflunomide:

Show Full Answer

What would you like to know about leflunomide?

Leflunomide, sold under the brand name Arava, is a disease-modifying antirheumatic drug (DMARD) used to treat rheumatoid arthritis. It works by targeting the immune system to reduce inflammation and slow down the progression of RA.

Here are some key points about leflunomide:

* It's classified as a conventional (synthetic) DMARD
* It helps control symptoms, prevent flare-ups, and prevent joint damage
* It can be prescribed alone or in combination with other RA medications

Potential Side Effects:

One notable side effect is hair loss, which affects up to 10% of people taking it. A myRAteam member shared their experience with hair changes while on treatment.

Leflunomide can also cause dry mouth as a side effect in some people.

Drug Interactions:

Taking NSAIDs (nonsteroidal anti-inflammatory drugs) with leflunomide might cause a buildup of NSAIDs in your body, potentially leading to additional side effects.

If you have specific questions about leflunomide, such as dosing, managing side effects, or how it compares to other treatments, feel free to ask!

November 25, 2025

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