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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 18, 2025
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A myRAteam Member

I've been on methotrexate 20 mgs once a week for a year now. My RA doctor
told me to skip my dose anytime I plan to get a vaccine. I think she said
it would make the vaccine less effective. Usually take it on Mondays
skipped it and got my flu vaccine on Thursday. Will probably start back on
MTX on Tuesday instead of Monday this time. She also told me anytime I
feel like I'm coming down with an illness to skip my dose.

October 18, 2025
COVID-19 and Rheumatoid Arthritis (RA) Essential Updates Read more >
myRAteam

The timing of RA medications after vaccination can affect vaccine effectiveness. Whether you should skip tomorrow's dose depends on which specific medication you're taking. Here are the general recommendations for common RA medications after vaccination:

• Methotrexate: Hold for one week after vaccination
• JAK inhibitors Show Full Answer

The timing of RA medications after vaccination can affect vaccine effectiveness. Whether you should skip tomorrow's dose depends on which specific medication you're taking. Here are the general recommendations for common RA medications after vaccination:

• Methotrexate: Hold for one week after vaccination
• JAK inhibitors (Rinvoq, Xeljanz): Hold for one week
• Rituximab: Hold for 2-4 weeks after second dose
• Cyclophosphamide: Schedule one week after vaccination
• Abatacept (Orencia): Hold for one week before and after first dose only
• Other RA medications: No need to change schedule Important: Please contact your rheumatologist before making any changes to your medication schedule. This is especially important if you're experiencing active disease symptoms. Your doctor can help determine the best approach based on your specific situation and current disease activity.

October 18, 2025
COVID-19 and Rheumatoid Arthritis (RA) Essential Updates Read more >
A myRAteam Member

😊 thanks. It's always a bit of a juggling act 🙂🙃

October 18, 2025
A myRAteam Member

What about tocilizumab (actemra)?

October 18, 2025
COVID-19 and Rheumatoid Arthritis (RA) Essential Updates Read more >

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