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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 14, 2025
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A myRAteam Member

Thats encouraging to hear. I'm just hoping the expertise of my doctor will help me feel good again. Thanks for giving me hope.

September 15, 2025
myRAteam

Yes, it is typical to try different biologics when one stops being effective or if you experience a flare. Actemra works differently than your previous medications - it targets inflammatory proteins called cytokines rather than targeting TNF-alpha like Enbrel, Remicade, and Cimzia.

Actemra can be used alone or combined Show Full Answer

Yes, it is typical to try different biologics when one stops being effective or if you experience a flare. Actemra works differently than your previous medications - it targets inflammatory proteins called cytokines rather than targeting TNF-alpha like Enbrel, Remicade, and Cimzia.

Actemra can be used alone or combined with other medications. One potential benefit is that it may work more quickly than other biologics - some people notice effects within 4-8 weeks of starting treatment. During this transition period, your doctor may recommend additional treatments to help manage flare symptoms, such as:

• Corticosteroids
• Over-the-counter pain relievers
• Using hot/cold therapy
• Getting extra rest
• Stress reduction techniques
• Light exercise (if approved by your doctor)

Work closely with your healthcare team to monitor how you respond to Actemra and manage any flare symptoms during the transition.

September 14, 2025
A myRAteam Member

@A myRAteam Member Sorry Enbrel stopped working for you. I was on Inflectra for almost 2 years and it stopped working. That is the longest any RA med has worked for me. I have also been on Erelzi (bio similar to Enbrel) only lasted 10 months, same for Hyrimoz (bio similar to Humira), and Orencia did not help at all and I have tried more. I recently started Actemra in May. I got a bit of a rash but RA doctor and GP doctor not sure if it from Actemra. I have my 5th dose this coming Friday so will see if the rash gets worse? Hope Actemra helps you.

September 14, 2025

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Sacramento, CA